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busulfan

Term Information

Accession
CHEBI:28901
Name
busulfan
Ontology
Synonyms
Busulfan, butane-1,4-diyl dimethanesulfonate, 1,4-Bis(methanesulfonoxy)butane, 1,4-Butanediol dimethanesulfonate, 1,4-Dimesyloxybutane, 1,4-Dimethanesulfonoxybutane, Bisulfex, Leucosulfan, Mablin, Mielucin, Misulban, Mitostan, Myeloleukon, Myleran, Tetramethylene bis(methanesulfonate), busulfan, busulfano, busulfanum
Alternate IDs
None
Definition
A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant. [source: unknown]
Comment
None
Subset
None
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Parents of busulfan (CHEBI:28901)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
busulfan [RO:0000087 relation] RO:0000087  teratogenic agent (CHEBI:50905)
busulfan [RO:0000087 relation] RO:0000087  carcinogenic agent (CHEBI:50903)
busulfan [has_functional_parent relation] has_functional_parent  butane-1,4-diol (CHEBI:41189)
busulfan [is_a relation] is_a  methanesulfonate ester (CHEBI:25223)
busulfan [RO:0000087 relation] RO:0000087  alkylating agent (CHEBI:22333)
busulfan [RO:0000087 relation] RO:0000087  antineoplastic agent (CHEBI:35610)
busulfan [RO:0000087 relation] RO:0000087  insect sterilant (CHEBI:67105)

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None.