Term Information

Accession
GO:1990926
Name
short-term synaptic potentiation
Ontology
biological_process
Synonyms
synaptic facilitation
Alternate IDs
None
Definition
The process by which synaptic transmission, induced by the arrival of a spike (action potential) at a synapse, acts to increase the amount of neurotransmitter released in response to the arrival of subsequent spikes. This effect is seen when a train of closely space spikes arrives at a synapse with a low initial release probability. It occurs in a timeframe of tens to hundreds of milliseconds. Source: PMID:26738595, GOC:sp, PMID:11826273, ISBN:9780071120005, GOC:dos
Comment
The mechanism of short term potentiation is thought to be either increased influx of calcium into the presynapse (Zucker and Regeh, 2002 PMID:11826273) increased sensitivity to calcium (Jackman et al., 2016 PMID:26738595) or both.
History
See term history for GO:1990926 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of short-term synaptic potentiation (GO:1990926)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
short-term synaptic potentiation [is_a relation] is_a  regulation of synaptic plasticity (GO:0048167)
Children of short-term synaptic potentiation (GO:1990926)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of short-term synaptic potentiation (GO:1905513) [RO:0002212 relation] RO:0002212  short-term synaptic potentiation
positive regulation of short-term synaptic potentiation (GO:1905514) [RO:0002213 relation] RO:0002213  short-term synaptic potentiation
regulation of short-term synaptic potentiation (GO:1905512) [RO:0002211 relation] RO:0002211  short-term synaptic potentiation
None.