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mitotic checkpoint complex, CDC20-MAD2 subcomplex

Term Information

Accession
GO:1990333
Name
mitotic checkpoint complex, CDC20-MAD2 subcomplex
Ontology
cellular_component
Synonyms
CDC20-MAD2 complex
Alternate IDs
None
Definition
A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20. Source: PMID:15879521, GOC:bhm
Comment
An example of this is cdc20 in Saccharomyces cerevisiae (P26309) in PMID:15879521 (inferred from direct assay).
History
See term history for GO:1990333 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of mitotic checkpoint complex, CDC20-MAD2 subcomplex (GO:1990333)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mitotic checkpoint complex, CDC20-MAD2 subcomplex [is_a relation] is_a  nuclear protein-containing complex (GO:0140513)
mitotic checkpoint complex, CDC20-MAD2 subcomplex [BFO:0000050 relation] BFO:0000050  mitotic checkpoint complex (GO:0033597)

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None.