Term Information

Accession
GO:0051304
Name
chromosome separation
Ontology
biological_process
Synonyms
chromatid release, rDNA separation
Alternate IDs
GO:0034500
Definition
The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II). Source: PMID:20352243, GOC:lb, GOC:mah, GOC:ai, GOC:mtg_cell_cycle
Comment
None
History
See term history for GO:0051304 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of chromosome separation (GO:0051304)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
chromosome separation [BFO:0000050 relation] BFO:0000050  chromosome segregation (GO:0007059)
chromosome separation [is_a relation] is_a  cell cycle process (GO:0022402)
Children of chromosome separation (GO:0051304)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mitotic sister chromatid separation (GO:0051306) [is_a relation] is_a  chromosome separation
negative regulation of chromosome separation (GO:1905819) [RO:0002212 relation] RO:0002212  chromosome separation
meiotic chromosome separation (GO:0051307) [is_a relation] is_a  chromosome separation
positive regulation of chromosome separation (GO:1905820) [RO:0002213 relation] RO:0002213  chromosome separation
regulation of chromosome separation (GO:1905818) [RO:0002211 relation] RO:0002211  chromosome separation
centromere separation (GO:0034510) [BFO:0000050 relation] BFO:0000050  chromosome separation
None.