Term Information

Accession
GO:0046222
Name
aflatoxin metabolic process
Ontology
biological_process
Synonyms
aflatoxin metabolism, aflatoxin B metabolic process
Alternate IDs
GO:0043389
Definition
The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450. Source: GOC:ai
Comment
None
History
See term history for GO:0046222 at QuickGO
Subset
None
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of aflatoxin metabolic process (GO:0046222)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
aflatoxin metabolic process [is_a relation] is_a  organic heteropentacyclic compound metabolic process (GO:1901376)
aflatoxin metabolic process [is_a relation] is_a  mycotoxin metabolic process (GO:0043385)
Children of aflatoxin metabolic process (GO:0046222)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
aflatoxin catabolic process (GO:0046223) [is_a relation] is_a  aflatoxin metabolic process
aflatoxin biosynthetic process (GO:0045122) [is_a relation] is_a  aflatoxin metabolic process
aflatoxin B2 metabolic process (GO:0043391) [is_a relation] is_a  aflatoxin metabolic process
aflatoxin B1 metabolic process (GO:0043390) [is_a relation] is_a  aflatoxin metabolic process
None.