Term Information

Accession
GO:0043197
Name
dendritic spine
Ontology
cellular_component
Synonyms
dendrite spine, branched dendritic spine, mushroom dendritic spine, sessile dendritic spine, stubby dendritic spine, thin dendritic spine
Alternate IDs
None
Definition
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity. Source: GOC:nln
Comment
None
History
See term history for GO:0043197 at QuickGO
Subset
goslim_synapse
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of dendritic spine (GO:0043197)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
dendritic spine [BFO:0000050 relation] BFO:0000050  dendrite (GO:0030425)
dendritic spine [is_a relation] is_a  postsynapse (GO:0098794)
dendritic spine [is_a relation] is_a  neuron spine (GO:0044309)
Children of dendritic spine (GO:0043197)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cytoskeleton of dendritic spine (GO:0098836) [BFO:0000050 relation] BFO:0000050  dendritic spine
thorny excrescence (GO:0097464) [is_a relation] is_a  dendritic spine
spine apparatus (GO:0097444) [BFO:0000050 relation] BFO:0000050  dendritic spine
dendritic spine neck (GO:0044326) [BFO:0000050 relation] BFO:0000050  dendritic spine
dendritic spine cytoplasm (GO:0061846) [BFO:0000050 relation] BFO:0000050  dendritic spine
dendritic spine head (GO:0044327) [BFO:0000050 relation] BFO:0000050  dendritic spine
NIF_Subcellular
sao1799103720
Wikipedia
Dendritic_spine