Term Information

Accession
GO:0038024
Name
cargo receptor activity
Ontology
molecular_function
Synonyms
endocytic receptor activity, receptor activity involved in receptor-mediated endocytosis, receptor activity, transport receptor activity
Alternate IDs
None
Definition
Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles. Source: PMID:15239958, PMID:27903609
Comment
Notes: (1) this term and its child terms are intended for receptors that bind to and internalize molecules by receptor-mediated endocytosis. For receptors that are coupled to a signal transduction pathway, consider instead the term 'signaling receptor activity ; GO:0038023' and its children. (2) Cargo receptors transport substances by vesicular transport, not by transmembrane transport. For transmembrane transporters, consider instead the term 'transmembrane transporter activity ; GO:0022857.
History
See term history for GO:0038024 at QuickGO
Subset
None
Feedback
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Parents of cargo receptor activity (GO:0038024)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cargo receptor activity [is_a relation] is_a  molecular_function (GO:0003674)
cargo receptor activity [BFO:0000051 relation] BFO:0000051  molecular adaptor activity (GO:0060090)
cargo receptor activity [BFO:0000050 relation] BFO:0000050  endocytosis (GO:0006897)
Children of cargo receptor activity (GO:0038024)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
lipoprotein particle receptor activity (GO:0030228) [is_a relation] is_a  cargo receptor activity
phagocytosis, recognition (GO:0006910) [BFO:0000051 relation] BFO:0000051  cargo receptor activity
lactoferrin receptor activity (GO:0033568) [is_a relation] is_a  cargo receptor activity
vitellogenin receptor activity (GO:0008196) [is_a relation] is_a  cargo receptor activity
apolipoprotein receptor activity (GO:0030226) [is_a relation] is_a  cargo receptor activity
alpha-2 macroglobulin receptor activity (GO:0016964) [is_a relation] is_a  cargo receptor activity
asialoglycoprotein receptor activity (GO:0004873) [is_a relation] is_a  cargo receptor activity
ferritin receptor activity (GO:0070287) [is_a relation] is_a  cargo receptor activity
heme receptor activity (GO:0140488) [is_a relation] is_a  cargo receptor activity
scavenger receptor activity (GO:0005044) [is_a relation] is_a  cargo receptor activity
transferrin receptor activity (GO:0004998) [is_a relation] is_a  cargo receptor activity
folic acid receptor activity (GO:0061714) [is_a relation] is_a  cargo receptor activity