Term Information

Accession
GO:0016829
Name
lyase activity
Ontology
molecular_function
Synonyms
other lyase activity
Alternate IDs
None
Definition
Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring. Source: EC:4.-.-.-, ISBN:0198547684
Comment
Note that enzymes of class EC:4.99.-.- should also be annotated to this term.
History
See term history for GO:0016829 at QuickGO
Subset
goslim_metagenomics
goslim_aspergillus
goslim_chembl
goslim_generic
goslim_candida
goslim_yeast
goslim_pir
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of lyase activity (GO:0016829)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
lyase activity [is_a relation] is_a  catalytic activity (GO:0003824)
Children of lyase activity (GO:0016829)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of lyase activity (GO:0051349) [RO:0002213 relation] RO:0002213  lyase activity
alkylmercury lyase activity (GO:0018836) [is_a relation] is_a  lyase activity
indoleacetaldoxime dehydratase activity (GO:0047720) [is_a relation] is_a  lyase activity
negative regulation of lyase activity (GO:0051350) [RO:0002212 relation] RO:0002212  lyase activity
cobalt-precorrin-5A acetaldehyde-lyase activity (GO:0043779) [is_a relation] is_a  lyase activity
sirohydrochlorin cobaltochelatase activity (GO:0016852) [is_a relation] is_a  lyase activity
carbon-oxygen lyase activity (GO:0016835) [is_a relation] is_a  lyase activity
carbon phosphorus lyase activity (GO:0018835) [is_a relation] is_a  lyase activity
regulation of lyase activity (GO:0051339) [RO:0002211 relation] RO:0002211  lyase activity
carbon-nitrogen lyase activity (GO:0016840) [is_a relation] is_a  lyase activity
carbon-carbon lyase activity (GO:0016830) [is_a relation] is_a  lyase activity
2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity (GO:0043729) [is_a relation] is_a  lyase activity
ferrochelatase activity (GO:0004325) [is_a relation] is_a  lyase activity
carbon-halide lyase activity (GO:0016848) [is_a relation] is_a  lyase activity
phosphorus-oxygen lyase activity (GO:0016849) [is_a relation] is_a  lyase activity
carbon-sulfur lyase activity (GO:0016846) [is_a relation] is_a  lyase activity
EC
4