Term Information

Accession
GO:0006898
Name
receptor-mediated endocytosis
Ontology
biological_process
Synonyms
receptor mediated endocytosis
Alternate IDs
None
Definition
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles. Source: ISBN:0716731363, GOC:mah
Comment
None
History
See term history for GO:0006898 at QuickGO
Subset
None
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of receptor-mediated endocytosis (GO:0006898)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
receptor-mediated endocytosis [is_a relation] is_a  endocytosis (GO:0006897)
Children of receptor-mediated endocytosis (GO:0006898)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
clathrin-dependent endocytosis (GO:0072583) [is_a relation] is_a  receptor-mediated endocytosis
negative regulation of receptor-mediated endocytosis (GO:0048261) [RO:0002212 relation] RO:0002212  receptor-mediated endocytosis
receptor internalization (GO:0031623) [is_a relation] is_a  receptor-mediated endocytosis
regulation of receptor-mediated endocytosis (GO:0048259) [RO:0002211 relation] RO:0002211  receptor-mediated endocytosis
cargo receptor activity (GO:0038024) [BFO:0000050 relation] BFO:0000050  receptor-mediated endocytosis
plasma lipoprotein particle clearance (GO:0034381) [BFO:0000051 relation] BFO:0000051  receptor-mediated endocytosis
receptor-mediated endocytosis involved in cholesterol transport (GO:0090118) [is_a relation] is_a  receptor-mediated endocytosis
endocytic hemoglobin import (GO:0020028) [is_a relation] is_a  receptor-mediated endocytosis
positive regulation of receptor-mediated endocytosis (GO:0048260) [RO:0002213 relation] RO:0002213  receptor-mediated endocytosis
receptor-mediated endocytosis of virus by host cell (GO:0019065) [is_a relation] is_a  receptor-mediated endocytosis