Term Information

Accession
GO:0006352
Name
DNA-templated transcription, initiation
Ontology
biological_process
Synonyms
DNA-dependent RNA polymerase complex assembly at promoter, DNA-dependent transcription, initiation, initiation of DNA-dependent transcription, initiation of transcription, DNA-dependent, transcription initiation factor activity, transcription initiation, DNA-dependent
Alternate IDs
None
Definition
Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription. Source: GOC:txnOH, GOC:jid, PMID:18280161
Comment
Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.
History
See term history for GO:0006352 at QuickGO
Subset
goslim_yeast
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of DNA-templated transcription, initiation (GO:0006352)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA-templated transcription, initiation [is_a relation] is_a  RNA biosynthetic process (GO:0032774)
DNA-templated transcription, initiation [BFO:0000050 relation] BFO:0000050  transcription, DNA-templated (GO:0006351)
Children of DNA-templated transcription, initiation (GO:0006352)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
transcription initiation from bacterial-type RNA polymerase promoter (GO:0001123) [is_a relation] is_a  DNA-templated transcription, initiation
transcription initiation from RNA polymerase I promoter (GO:0006361) [is_a relation] is_a  DNA-templated transcription, initiation
regulation of DNA-templated transcription, initiation (GO:2000142) [RO:0002211 relation] RO:0002211  DNA-templated transcription, initiation
positive regulation of DNA-templated transcription, initiation (GO:2000144) [RO:0002213 relation] RO:0002213  DNA-templated transcription, initiation
DNA-templated transcriptional start site selection (GO:0001173) [BFO:0000050 relation] BFO:0000050  DNA-templated transcription, initiation
negative regulation of DNA-templated transcription, initiation (GO:2000143) [RO:0002212 relation] RO:0002212  DNA-templated transcription, initiation
DNA-templated transcriptional open complex formation (GO:0001112) [BFO:0000050 relation] BFO:0000050  DNA-templated transcription, initiation
transcription initiation from mitochondrial promoter (GO:0006391) [is_a relation] is_a  DNA-templated transcription, initiation
transcription initiation from RNA polymerase III promoter (GO:0006384) [is_a relation] is_a  DNA-templated transcription, initiation
transcription preinitiation complex assembly (GO:0070897) [BFO:0000050 relation] BFO:0000050  DNA-templated transcription, initiation
transcription initiation from RNA polymerase II promoter (GO:0006367) [is_a relation] is_a  DNA-templated transcription, initiation
None.