Term Information

Accession
GO:0005044
Name
scavenger receptor activity
Ontology
molecular_function
Synonyms
macrophage receptor activity
Alternate IDs
None
Definition
Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, amyloid-beta fibrils, and advanced glycation end products (AGEs). Source: PMID:12379907, PMID:12621157, GOC:bf, PMID:20981357, PMID:11790542
Comment
Note that many gene products that are called scavenger receptors have a broad range of potential ligands and also can be annotated to 'pattern recognition receptor activity ; GO:0038187' or its child terms, or to 'lipoprotein receptor activity ; GO:0030228' or its child terms. For receptors that transduce a signal rather than endocytose their ligand, consider instead the terms 'signaling receptor activity ; GO:0038023' and its children.
History
See term history for GO:0005044 at QuickGO
Subset
goslim_chembl
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of scavenger receptor activity (GO:0005044)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
scavenger receptor activity [is_a relation] is_a  cargo receptor activity (GO:0038024)

This term has no children.

None.