Term Information

Accession
GO:0002467
Name
germinal center formation
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation. Source: GO_REF:0000022, ISBN:081533642X, GOC:jal
Comment
None
History
See term history for GO:0002467 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of germinal center formation (GO:0002467)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
germinal center formation [is_a relation] is_a  adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002460)
germinal center formation [is_a relation] is_a  anatomical structure formation involved in morphogenesis (GO:0048646)
Children of germinal center formation (GO:0002467)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of germinal center formation (GO:0002636) [RO:0002213 relation] RO:0002213  germinal center formation
regulation of germinal center formation (GO:0002634) [RO:0002211 relation] RO:0002211  germinal center formation
negative regulation of germinal center formation (GO:0002635) [RO:0002212 relation] RO:0002212  germinal center formation
None.