Term Information

Accession
GO:0001181
Name
RNA polymerase I general transcription initiation factor activity
Ontology
molecular_function
Synonyms
RNA polymerase I transcription general initiation factor activity, general RNA polymerase I transcription factor activity, core RNA polymerase I binding transcription factor activity, transcription factor activity, core RNA polymerase I binding
Alternate IDs
None
Definition
A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase I. Factors required for RNA polymerase I transcription initiation include upstream activation factor (UAF), core factor (CF), TATA binding protein (TBP) and RRN3. In all species characterized, RNA polymerase I transcribes a large polycistronic transcript that is processed into several mature rRNAs (3 or 4 depending on the species), including the large subunit rRNA (28S in humans), the small subunit rRNA (18S in humans), as well as one or two additional smaller rRNAs (the 5.8S rRNA in humans). In most species, this large rRNA transcript is the sole product of RNA polymerase I. However there are rare exceptions, such as Trypanosoma brucei, where RNA polymerase I also transcribes certain mRNAs. Source: GOC:txnOH-2018, PMID:11500378, PMID:31358304, PMID:28340337, PMID:17972917, PMID:25346433, PMID:28842442
Comment
None
History
See term history for GO:0001181 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of RNA polymerase I general transcription initiation factor activity (GO:0001181)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
RNA polymerase I general transcription initiation factor activity [BFO:0000050 relation] BFO:0000050  transcription by RNA polymerase I (GO:0006360)
RNA polymerase I general transcription initiation factor activity [is_a relation] is_a  general transcription initiation factor activity (GO:0140223)

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None.