Term Information

Accession
GO:0000981
Name
DNA-binding transcription factor activity, RNA polymerase II-specific
Ontology
molecular_function
Synonyms
RNA polymerase II transcription factor activity, sequence-specific DNA binding, RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity
Alternate IDs
GO:0001133
Definition
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units. Source: GOC:txnOH-2018
Comment
Merged terms see https://github.com/geneontology/go-ontology/issues/15530; Changed term label and definition https://github.com/geneontology/go-ontology/issues/16131
History
See term history for GO:0000981 at QuickGO
Subset
None
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA-binding transcription factor activity, RNA polymerase II-specific [BFO:0000050 relation] BFO:0000050  regulation of transcription by RNA polymerase II (GO:0006357)
DNA-binding transcription factor activity, RNA polymerase II-specific [is_a relation] is_a  DNA-binding transcription factor activity (GO:0003700)
DNA-binding transcription factor activity, RNA polymerase II-specific [BFO:0000066 relation] BFO:0000066  nuclear chromatin (GO:0000790)
Children of DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding (GO:0000982) [is_a relation] is_a  DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific (GO:0001228) [is_a relation] is_a  DNA-binding transcription factor activity, RNA polymerase II-specific
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding (GO:0003705) [is_a relation] is_a  DNA-binding transcription factor activity, RNA polymerase II-specific
nuclear receptor activity (GO:0004879) [is_a relation] is_a  DNA-binding transcription factor activity, RNA polymerase II-specific
transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding (GO:0000983) [is_a relation] is_a  DNA-binding transcription factor activity, RNA polymerase II-specific
RNA polymerase II transcription factor activity, metal ion regulated sequence-specific DNA binding (GO:0001200) [is_a relation] is_a  DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription repressor activity, RNA polymerase II-specific (GO:0001227) [is_a relation] is_a  DNA-binding transcription factor activity, RNA polymerase II-specific
None.