Term Information

Accession
GO:0000075
Name
cell cycle checkpoint
Ontology
biological_process
Synonyms
G1/S checkpoint, G1/S transition checkpoint, G2/M checkpoint, G2/M transition checkpoint
Alternate IDs
GO:0071779, GO:0031576
Definition
A cell cycle process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction. Source: GOC:mtg_cell_cycle
Comment
This term should not be used in direct manual annotation as it should always be possible to minimally designate mitotic or meiotic checkpoint, and usually to additionally specify the checkpoint (i.e mitotic spindle assembly checkpoint, mitotic DNA damage checkpoint etc). Note also that the effector processes are not part of the checkpoint but are positively regulated by the checkpoint signaling and should not be annotated here.
History
See term history for GO:0000075 at QuickGO
Subset
gocheck_do_not_manually_annotate
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of cell cycle checkpoint (GO:0000075)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cell cycle checkpoint [is_a relation] is_a  negative regulation of cell cycle (GO:0045786)
cell cycle checkpoint [BFO:0000051 relation] BFO:0000051  signal transduction (GO:0007165)
cell cycle checkpoint [is_a relation] is_a  cellular process (GO:0009987)
Children of cell cycle checkpoint (GO:0000075)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
detection of stimulus involved in cell cycle checkpoint (GO:0072394) [BFO:0000050 relation] BFO:0000050  cell cycle checkpoint
signal transduction involved in cell cycle checkpoint (GO:0072395) [BFO:0000050 relation] BFO:0000050  cell cycle checkpoint
regulation of cell cycle checkpoint (GO:1901976) [RO:0002211 relation] RO:0002211  cell cycle checkpoint
spindle checkpoint (GO:0031577) [is_a relation] is_a  cell cycle checkpoint
negative regulation of cell cycle checkpoint (GO:1901977) [RO:0002212 relation] RO:0002212  cell cycle checkpoint
DNA integrity checkpoint (GO:0031570) [is_a relation] is_a  cell cycle checkpoint
mitotic cell cycle checkpoint (GO:0007093) [is_a relation] is_a  cell cycle checkpoint
positive regulation of cell cycle checkpoint (GO:1901978) [RO:0002213 relation] RO:0002213  cell cycle checkpoint
meiotic cell cycle checkpoint (GO:0033313) [is_a relation] is_a  cell cycle checkpoint